Biotechnology development (+CILS), including site visit @ LightChainBio offices in Plan-les-Ouates. - Modified as follows: lectures maintained using Microsoft Teams (managed by LightChainBio), no site visit for the moment

Monday 4 may 2020, 8:30-12:00 and 13:30-15:15; Tuesday 5 may 2020, 8:30-12:00 and 13:30-15:00; Tuesday 12 may 2020, @ LightChainBio Offices, in Plan les Ouates, from 09:00 to 18:00 (approx.)

Responsable du cours: Dr Walter FERLIN, LightChainBio

Organisatrice: Mme Leticia BARBA, LightChainBio

Mr Pierre AZOULAY (LCB)

Mme Leticia BARBA (LCB)

Dr Xavier CHAUCHET (LCB)

Dr Walter FERLIN (LCB)

Dr Nicolas FISCHER (LCB)

Dr Hasnaà HADDOUK (SOBI)

Dr Adrian HAINES (SOBI)

Dr Eric HATTERER (LCB)

Mr Giovanni MAGISTRELLI (LCB)

Dr Emmanuel MONNET (SOBI)

Dr Robert NELSON (Covance)

Mme Jenna SALTI (LCB)

Dr Laetitia SORDE (SOBI)

Course Outline:

· Overview of the steps for drug development (2h, EM)

· Introduction to bioanalysis and clinical sample testing (1h, RN)

· Immunogenicity of biotherapeutics (1h, LS)

· Toolbox to streamline the identification of Antibody Drug Candidate (1h, GM)

· Manufacturing antibodies (1h, AH)

· TBD (2h, XC)

· Preclinical drug development: in vitro and in vivo pharmacology (2h, EH)

· Non-Clinical Safety Requirements before First in Human (2h, HH)

· Supporting Biotechs: the role of QA (0.5h, JS and PA)

· Supporting Biotechs: the role of Project Management (1h, LB)

· Bringing an antibody program from a concept to patients (2h, WF)

· Therapeutic antibody formats and discovery platforms (2h, NF)

4 and 5 may: UNIGE, CMU, room A04.2713 and 12 may: Plan les Ouates, chemin des Aulx, @LightChainBio offices

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