Monitoring of leachables in hospital pharmacy compounding

Title: Monitoring of leachables in hospital pharmacy compounding

- Built of a new concept of monitoring leachable compounds in Hospital Pharmacy by suggesting implementation of workflows and analytics.

- Development of a non-volatile compound screening (semiquantitative analysis) via UHPLC-HRMS via post-column infusion

- Development of an in-house knowledge-based database for the identification, semiquantitation and toxicological assessment of leachable compounds in hospital pharmacy-compounded drug products

- Development of a generic sample preparation via DLLME for high enrichment and low solvent consumption

- Application of all of the above on diverse hospital pharmacy compoundings to bring about the monitoring of leachable compounds and their safety risk assessments.