RMN

30 et 31 janvier 2017, de 9 à 16h

Dr. Pascal Miéville, EPFL

Dr. Pascal Miéville, EPFL

Goal :

Giving to participants a basic understanding of the existing fundamental theories and models underlying NMR spectroscopy. Then based on this understanding, developing a description of the most common mono and multidimensional NMR experiments. A strong focus will be put on understanding the information that can be extracted using these different experiments and also to their respective limits. During the lecture, some practical demonstration will be presented directly on a NMR spectrometer and participants will have the opportunity to practice some spectrum processing and resolution directly on their own laptop.

Detailed content :

- Very basic aspects of quantum mechanic (nucleus, spins).

- A general image of spectroscopy and more precisely resonance spectroscopies.

- What happens to a real sample in the spectrometer - Vector model.

- From the model to the 1D spectrum.

- Practical aspects of acquisition and processing of a NMR spectrum - applied session.

- From 1D spectra to a simple structure.

- What happens if the structure is a bit more complex - 2D NMR.

- Description of the most typical 2D NMR experiments.

- From a set of 1D and 2D spectra to a little more complex structure.

- How to get rid of this big solvent peak ?

- NMR can do chromatography - DOSY.

- Some recent NMR developments in various fields.

- Open discussion and questions.

CMU Genève, SALLE B08.2225

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